Quinolones News

#2 April 20, 2012

A U.K. study shows that H. pylori surveillance is necessary to guide dyspepsia mangement.

Most patients are prescribed H. pylori treatment without culture and antibiotic susceptibility testing and a group in the Primary Care Unit, Health Protection Agency, Gloucester Royal Hospital, Gloucester, U.K., carried out a study to determine the incidence of H. pylori resistance in patients receiving an endoscopy in England and Wales.
The study involved 2,063 patients in Gloucester and Bangor hospitals and H. pylori was cultured in 6.4%. Quinolone resistance was significantly lower than resistance to clarithromycin and metronidazole. The authors believe a surveillance system should be used to help guide dyspepsia management.

PMID: 22469191

Aliment Pharmacol Ther. 2012 Apr 2. [Epub ahead of print]

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